Disease Surveillance: South Africa’s foot-and-mouth crisis is worsening because there’s no mandatory nationwide system to trace outbreaks, leaving farmers and authorities to rely on patchy local tracking; a recent SAT2 outbreak since 2021 has spread across provinces and is projected to cost the livestock sector billions in lost production and export revenue. Patent Watch: Pan African Treatment Access Movement and Third World Network have filed a third-party observation at ARIPO challenging a broad Gilead patent application on HIV compounds, arguing earlier disclosures and prior science undermine novelty. AI in Health & Apps (Eswatini): MTN Eswatini is pushing digital health via the Notsa Health App, including Siswati localisation and training with Georgetown University to help users manage reminders and health information. AI in Browsers (Africa): Google is expanding “Ask Gemini in Chrome” to Kenya, Nigeria and South Africa, with Eswatini included in the broader rollout list. Higher Education Tech Cooperation (Eswatini–SA): Eswatini’s PM reaffirmed plans with South Africa to deepen collaboration in higher education, science, innovation and ICT, including work toward a SADC University of Technology. Next-Gen TB Diagnostics (Eswatini): Researchers in Eswatini used targeted next-generation sequencing to detect rifampicin and bedaquiline resistance missed by routine tests, pointing to better MDR-TB treatment targeting. Border Anti-Corruption (SA–Eswatini): South Africa’s Border Management Authority and the SIU stepped up anti-corruption at Oshoek Port of Entry, using former officials’ prison accounts to expose fraud networks.